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Synthesis of Two LewisX Trisaccharides Using Regiospecific Glycosylation Reactions

IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata

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Title Synthesis of Two LewisX Trisaccharides Using Regiospecific Glycosylation Reactions
 
Creator Mukherjee, Debaraj
Sarkar, Sujit Kumar
Chattopadhyay, Partha
Chowdhury, Uday Shankar
 
Subject Chemistry
 
Description Synthesis of two LewisX trisaccharides, namely, 2-(trimethylsilyl)ethyl 2,3,4,6-tetra- O-acetyl-b-D-galactopyranosyl-(1!4)-6-O-benzyl-2-deoxy-3-O-(2,3,4-tri-O-benzyl-a-Lfucopyranosyl)- 2-phthalimido-b-D-glucopyranoside and 2-(trimethylsilyl)ethyl 2,3,4-tri- O-acetyl-6-O-t-butyldiphenylsilyl-b-D-galactopyranosyl-(1!4)-6-O-benzyl-2-deoxy-3-O- (2,3,4-tri-O-benzyl-a-L-fucopyranosyl)-2-phthalimido-b-D-glucopyranoside, has been achieved using a regiospecific glycosylation strategy under NIS-TfOH activation. Two trisaccharides were prepared from monosaccharides without any protecting group manipulation
 
Publisher Taylor & Francis
 
Date 2005
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://www.eprints.iicb.res.in/513/1/JOURNAL_OF_CARBOHYDRATE_CHEMISTRY_24(_3)_251%2D259;2005[78].pdf
Mukherjee, Debaraj and Sarkar, Sujit Kumar and Chattopadhyay, Partha and Chowdhury, Uday Shankar (2005) Synthesis of Two LewisX Trisaccharides Using Regiospecific Glycosylation Reactions. Journal of Carbohydrate Chemistry, 24 (3). pp. 251-259. ISSN 0732-8303
 
Relation http://dx.doi.org/10.1081/CAR-200058529
http://www.eprints.iicb.res.in/513/