Genomic structures and population histories of linguistically distinct tribal groups of India
IR@IICB: CSIR-Indian Institute of Chemical Biology, KolkataView Archive Info
Genomic structures and population histories
of linguistically distinct tribal groups of India
Usha Rani, M V
Sil, Samir K
Majumder, Partha P
Molecular & Human Genetics
There are various conflicting hypotheses regarding
the origins of the tribal groups of India, who belong
to three major language groups – Austro-Asiatic,
Dravidian and Tibeto-Burman. To test some of the major
hypotheses we designed a genetic study in which we sampled
tribal populations belonging to all the three language
groups. We used a set of autosomal DNA markers, mtDNA
restriction-site polymorphisms (RSPs) and mtDNA hypervariable
segment-1 (HVS-1) sequence polymorphisms in
this study. Using the unlinked autosomal markers we
found that there is a fair correspondence between linguistic
and genomic affinities among the Indian tribal groups.
We reconstructed mtDNA RSP haplotypes and found that
there is extensive haplotype sharing among all tribal populations.
However, there is very little sharing of mtDNA
HVS-1 sequences across populations, and none across language
groups. Haplogroup M is ubiquitous, and the subcluster
U2i of haplogroup U occurs in a high frequency.
Our analyses of haplogroup and HVS-1 sequence data
provides evidence in support of the hypothesis that the
Austro-Asiatic speakers are the most ancient inhabitants
of India. Our data also support the earlier finding that
some of the western Eurasian haplogroups found in India
may have been present in India prior to the entry of Aryan
speakers. However, we do not find compelling evidence
to support the theory that haplogroup M was brought into
India on an “out of Africa” wave of migration through a
southern exit route from Ethiopia. On the contrary, our
data raise the possibility that this haplogroup arose in India and was later carried to East Africa from India.
Roychoudhury, Susanta and Roy, Sangita and Basu, Analabha and Banerjee, Rajat and Vishwanathan, H and Usha Rani, M V and Sil, Samir K and Mitra, Mitashree and Majumder, Partha P (2001) Genomic structures and population histories of linguistically distinct tribal groups of India. Human Genetics, 109 (3). pp. 339-350.