CSIR Central

Allyl tetrahydropyranyl ether: a versatile alcohol/thiol protecting reagent

IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu

View Archive Info
 
 
Field Value
 
Title Allyl tetrahydropyranyl ether: a versatile alcohol/thiol protecting reagent
 
Creator Kumar, Brijesh
Aga, Mushtaq A.
Mukherjee, Debaraj
Chimni, Swapandeep S.
Taneja, Subhash C.
 
Subject Chemical Sciences
 
Description Allyl tetrahydropyranyl ether (ATHPE) can be used as a versatile protecting reagent. In combination with NBS/I2, O-allyl group can easily be replaced by hydroxyls (including tertiary-OH) or thiols, in the molecules comprising other reactive functional groups such as halogen, nitro, acetonide and alkene under mild reaction conditions (near neutral pH and ambient temperature).
 
Date 2009
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://iiim.csircentral.net/203/1/10.1016j.tetlet.2009.09.026.pdf
Kumar, Brijesh and Aga, Mushtaq A. and Mukherjee, Debaraj and Chimni, Swapandeep S. and Taneja, Subhash C. (2009) Allyl tetrahydropyranyl ether: a versatile alcohol/thiol protecting reagent. Tetrahedron Letters, 50 (46). pp. 6236-6240. ISSN 00404039
 
Relation http://dx.doi.org/10.1016/j.tetlet.2009.09.026
http://iiim.csircentral.net/203/