Tuftsin-bearing liposomes as drug vehicles in the treatment of experimental aspergillosis.
IR@IMTECH: CSIR-Institute of Microbial Technology, Chandigarh
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| Title |
Tuftsin-bearing liposomes as drug vehicles in the treatment of experimental aspergillosis.
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| Creator |
Owais, M
Ahmed, I Krishnakumar, B Jain, R K Bachhawat, B K Gupta, C M |
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| Subject |
QR Microbiology
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| Description |
Encapsulation of amphotericin B in tuftsin-bearing liposomes greatly increased its efficacy in treatment of human aspergillosis in mice. Also, the drug efficacy was significantly increased by pretreating the animals with drug-free tuftsin-bearing liposomes. These results demonstrate that macrophage activation can considerably enhance the therapeutic efficacy of antifungal drugs, like amphotericin B.
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| Publisher |
Elsevier Science
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| Date |
1993-07-12
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://crdd.osdd.net/open/417/1/gupta93.pdf
Owais, M and Ahmed, I and Krishnakumar, B and Jain, R K and Bachhawat, B K and Gupta, C M (1993) Tuftsin-bearing liposomes as drug vehicles in the treatment of experimental aspergillosis. FEBS letters, 326 (1-3). pp. 56-8. ISSN 0014-5793 |
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| Relation |
http://www.sciencedirect.com/science/article/pii/001457939381760W#bCOR1
http://crdd.osdd.net/open/417/ |
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