Biotransformations of rifamycins: process possibilities.
IR@IMTECH: CSIR-Institute of Microbial Technology, Chandigarh
View Archive Info| Field | Value | |
| Title |
Biotransformations of rifamycins: process possibilities.
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| Creator |
Banerjee, U C
Saxena, B Chisti, Y. |
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| Subject |
QD Chemistry
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| Description |
Rifampicin, an important antibiotic, is manufactured by chemical conversion of rifamycin S which is obtained by the chemical modification of rifamycin B. Rifamycin B is a product of Nocardia mediterranei fermentations. The chemical conversion of rifamycin B to rifamycin S has many disadvantages: Strong acidic conditions are required, heavy foam formation accompanies transformation and the yields are low. This review highlights the developments in alternative, biochemical transformations using enzymes and cells; the main focus is on transformations carried out by rifamycin oxidase.
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| Publisher |
Elsevier Science
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| Date |
1992
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://crdd.osdd.net/open/425/1/banerjee92.pdf
Banerjee, U C and Saxena, B and Chisti, Y. (1992) Biotransformations of rifamycins: process possibilities. Biotechnology advances, 10 (4). pp. 577-95. ISSN 0734-9750 |
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| Relation |
http://www.sciencedirect.com/science/article/pii/073497509291454M
http://crdd.osdd.net/open/425/ |
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