Prediction of guide strand of microRNAs from its sequence and secondary structure.
IR@IMTECH: CSIR-Institute of Microbial Technology, Chandigarh
View Archive Info| Field | Value | |
| Title |
Prediction of guide strand of microRNAs from its sequence and secondary structure.
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| Creator |
Ahmed, Firoz
Ansari, Hifzur Rahman Raghava, G.P.S. |
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| Subject |
QH301 Biology
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| Description |
In this study, first time a method has been developed to predict guide miRNA strands, of miRNA duplex. This study demonstrates that guide and passenger strand of miRNA precursors can be distinguished using their nucleotide sequence and secondary structure. This method will be useful in understanding microRNA processing and can be implemented in RNA silencing technology to improve the biological and clinical research. A web server has been developed based on SVM models described in this study (http://crdd.osdd.net:8081/RISCbinder/).
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| Publisher |
BIomedcentral
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| Date |
2009
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://crdd.osdd.net/open/562/1/raghava09.pdf
Ahmed, Firoz and Ansari, Hifzur Rahman and Raghava, G.P.S. (2009) Prediction of guide strand of microRNAs from its sequence and secondary structure. BMC bioinformatics, 10. p. 105. ISSN 1471-2105 |
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| Relation |
http://www.biomedcentral.com/1471-2105/10/105
http://crdd.osdd.net/open/562/ |
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