Expeditious synthesis of 5,6,7 ,8-tetrahydro-imidazo[1,2-a ] pyrimidin-2-ones and 3,4,6,7 ,8,9-hexahydro-pyrimido[,2-a ] pyrimidin-2-ones
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Pathak, Richa
Batra, Sanjay |
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| Date |
2007-11-30T06:53:33Z
2007-11-30T06:53:33Z 2007 |
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| Identifier |
Tetrahedron 63 (2007) 9448-9455
http://hdl.handle.net/123456789/35 |
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| Description |
A convenient synthesis of new 5,6,7 ,8-tetrahydro-imidazo[ 1,2-a]pyrimidin-2-ones and 3,4,6,7 ,8,9-hexahydro-pyrimido[1 ,2a]pyrimidin-2-
ones from the Baylis-Hillman adducts of acrylonitrile and their derivatives is described. A common strategy employed to achieve the syntheses of title
compounds involved generation of diamines from different Baylis-Hillman derivatives followed by treatment with cyanogen bromide at reflux
temperature to trigger a double intramolecular cyclization.
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188813 bytes
application/pdf |
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| Language |
en
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| Relation |
CDRI communication no. 7163
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| Title |
Expeditious synthesis of 5,6,7 ,8-tetrahydro-imidazo[1,2-a ] pyrimidin-2-ones and 3,4,6,7 ,8,9-hexahydro-pyrimido[,2-a ] pyrimidin-2-ones
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Article
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