Simple and efficient synthesis of substituted 2-pyrrolidinones, 2-pyrrolones and pyrrolidines from enaminones of Baylis-Hillman derivatives of 3-isoxazolecarbaldehydes
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
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Creator |
Singh, Vijay
Saxena, Rashmi Batra, Sanjay |
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Date |
2007-12-26T09:17:15Z
2007-12-26T09:17:15Z 2005 |
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Identifier |
Journal of Organic Chemistry, 70, 353-356 (2005)
http://hdl.handle.net/123456789/47 |
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Description |
The enaminones, generated from derivatives of appropriately substituted Baylis-Hillman adducts of 3-isoxazolecarbaldehydes undergo intramolecular ring-closure reactions to afford substituted 2-pyrrolidinones, 1,5-dihydro-2-pyrrolones and N-substituted pyrrolidines in good yields.
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Format |
125696 bytes
application/pdf |
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Language |
en
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Relation |
CDRI Communication No. 6651
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Subject |
Baylis-Hillman
3-isoxazolecarbaldehyde enaminone hydrogenation 2-pyrrolidinones 1,5-dihydro-2-pyrrolones N-substituted pyrrolidines |
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Title |
Simple and efficient synthesis of substituted 2-pyrrolidinones, 2-pyrrolones and pyrrolidines from enaminones of Baylis-Hillman derivatives of 3-isoxazolecarbaldehydes
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Type |
Article
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