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Simple and efficient synthesis of substituted 2-pyrrolidinones, 2-pyrrolones and pyrrolidines from enaminones of Baylis-Hillman derivatives of 3-isoxazolecarbaldehydes

IR@CDRI: CSIR-Central Drug Research Institute, Lucknow

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Field Value
 
Creator Singh, Vijay
Saxena, Rashmi
Batra, Sanjay
 
Date 2007-12-26T09:17:15Z
2007-12-26T09:17:15Z
2005
 
Identifier Journal of Organic Chemistry, 70, 353-356 (2005)
http://hdl.handle.net/123456789/47
 
Description The enaminones, generated from derivatives of appropriately substituted Baylis-Hillman adducts of 3-isoxazolecarbaldehydes undergo intramolecular ring-closure reactions to afford substituted 2-pyrrolidinones, 1,5-dihydro-2-pyrrolones and N-substituted pyrrolidines in good yields.
 
Format 125696 bytes
application/pdf
 
Language en
 
Relation CDRI Communication No. 6651
 
Subject Baylis-Hillman
3-isoxazolecarbaldehyde
enaminone
hydrogenation
2-pyrrolidinones
1,5-dihydro-2-pyrrolones
N-substituted pyrrolidines
 
Title Simple and efficient synthesis of substituted 2-pyrrolidinones, 2-pyrrolones and pyrrolidines from enaminones of Baylis-Hillman derivatives of 3-isoxazolecarbaldehydes
 
Type Article