An efficient substituent dependent synthesis of congested pyridines and pyrimidines
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
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Creator |
Pratap, Ramendra
Kumar, Brijesh Ram, Vishnu Ji |
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Date |
2007-12-27T09:43:55Z
2007-12-27T09:43:55Z 2007 |
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Identifier |
Tetrahedron 63 (2007) 10309-10319
http://hdl.handle.net/123456789/61 |
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Description |
An efficient and versatile synthesis of various congested pyridines 3a-h, 6a,b, 8a-n, lOa-g, and 16a,b, and (pyrimidin-4-yl)acetonitriles 13a-g
has been delineated by base catalyzed ring transformation of suitably functionalized 2H-pyran-2-ones la-h, 5, 7, and 15 by formamidine acetate 2a,acetamidine hydrochloride 2b, S-methylisothiourea 9a, pyrazol-I-yl-carboxamidine 9b, and arylamidine hydrochloride 12 separately in the presence of powdered KOH in dry DMF.
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Format |
444817 bytes
application/pdf |
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Language |
en
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Relation |
CDRI Communication No. 7078
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Title |
An efficient substituent dependent synthesis of congested pyridines and pyrimidines
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Type |
Article
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