Functional Drug Targeting to Erythrocytes In Vivo using Antibody Bearing Liposome as Drug Vehicles
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
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Creator |
Agrawal, Ajay K
Singhal, Arun Gupta, C M |
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Date |
2008-03-26T07:36:42Z
2008-03-26T07:36:42Z 1987 |
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Identifier |
Biochemical and Biophysical Research Communications (1987), 148, 357-361
http://hdl.handle.net/123456789/123 |
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Description |
Covalent attachment of anti-erythrocyte F(ab')2 to the liposome surface has recently been shown to considerably enhance tne liposome binding to erythrocytes in vivo. These antibody bearing liposomes have nPW been found quite effect1ve-as-vehicles for delivering the antimalarial drug., chloroquine. to erythrocytes in Plasmodium berghei-infected mice. This demonstrates
the usefulness of antibody targeted liposomes as carriers for site-specific
drug de1ivery.
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Format |
1390899 bytes
application/pdf |
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Language |
en
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Relation |
CDRI Communication No. 4131
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Title |
Functional Drug Targeting to Erythrocytes In Vivo using Antibody Bearing Liposome as Drug Vehicles
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Type |
Article
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