Enhancement in anti-Semliki Forest virus activity of ds RNA by a muramyl dipeptide
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
George, C X
Jain, Rakesh K Gupta, C M Anand, Nitya |
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| Date |
2008-03-26T07:37:30Z
2008-03-26T07:37:30Z 1986 |
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| Identifier |
FEBS Letters (1985), 200, 37-41
http://hdl.handle.net/123456789/125 |
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| Description |
Antiviral activity of an interferon-inducing mycoviral ds RNA against Semliki Forest virus infection was considerably enhanced by N-palmitoylmuramyl-L-alanyl-D-isoglutamine (PMDP), a new muramyl dipeptide. This enhancement in activity was not due to increased production of interferon, but resulted probably from a PMDP-induced increase in nonspecific resistance to infection. These results indicate that a combined
treatment with an interferon inducer and muramyl dipeptide may prove highly useful to control effectively viral infections.
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| Format |
1707276 bytes
application/pdf |
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| Language |
en
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| Relation |
CDRI Communication No.3790
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| Subject |
Viral infection
Interferon inducer Muramyl dipeptide Macrophage activation |
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| Title |
Enhancement in anti-Semliki Forest virus activity of ds RNA by a muramyl dipeptide
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| Type |
Article
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