Protection of mice against Plasmodium berghei infection by a tuftsin derivative
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Gupta, C M
Puri, Anju Jain, Rakesh K Bali, Anu Anand, Nitya |
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| Date |
2008-03-26T07:38:11Z
2008-03-26T07:38:11Z 1986 |
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| Identifier |
FEBS Letters (1986), 205, 351-354
http://hdl.handle.net/123456789/127 |
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| Description |
In Plasmodium berghei infections, the mortality rate and parasitacmias were significantly reduced and the
mean survival time was considerably enhanced by pretreating the animals with a tuftsin derivative, Thr-Lys-
Pro-Arg-NH-(CH2)2-NHCOC15H31. This effect of the modified tuftsin was further increased upon its incorporation
in the liposome bilayer. These results indicate that tuftsin and its derivatives may prove useful
in enhancing nonspecific host resistance against protozoan infections.
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| Format |
1549211 bytes
application/pdf |
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| Language |
en
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| Relation |
CDRI Communication No. 2929
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| Subject |
Protozoan infection
Immunomodulation Tuftsin Liposome Macrophage |
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| Title |
Protection of mice against Plasmodium berghei infection by a tuftsin derivative
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| Type |
Article
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