CSIR Central

DNA Microarray Data Management and Analysis :A General Framework

IR@CDRI: CSIR-Central Drug Research Institute, Lucknow

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Field Value
 
Creator Abbas, M
Mandal, S K
Srivastava, M
 
Date 2009-09-09T06:07:36Z
2009-09-09T06:07:36Z
2006
 
Identifier Statistical Advances in Biosciences & Bioinfomatics-2006-17-24.
81-7764-968-X
http://hdl.handle.net/123456789/510
 
Description DNA microarrays have emerged as the premier tool for studying gene expression on a genomics scale. They provide a format for the simultaneous measurements of the expression levels of thousands of genes in a single hybridization array. Scientists seeking to harness the potential of this technique are challenged by the large quantities of data produced. For tracking, integrating, qualifying and ultimately deriving scientific insight from the experimental results, various tools are required. In general, a well designed database, an interface for data entry and query, an image analysis software, normalization and filtering routines and software for data analysis and visualization are needed. For data analysis, various statistical and machine learning techniques have been applied. The main task is making groups of genes having the similar expression pattern. For this, methods such as hierarchical clustering, k-means clustering, self organizing maps, neural fretwork, support vector machine etc have been applied.
 
Format 5457589 bytes
application/pdf
 
Language en
 
Publisher Allied Publishers Private Limited, New Delhi
 
Title DNA Microarray Data Management and Analysis :A General Framework
 
Type Book