Application of Nazarov cyclization to access [6-5-6] and [6-5-5]tricyclic core embedded New Heterocycles : An easy entry to structures related to Taiwaniaquinoids
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Singh, Ritesh
Parai, M K Panda, Gautam |
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| Date |
2010-09-09T08:52:22Z
2010-09-09T08:52:22Z 2009 |
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| Identifier |
Org. Biomol. Chem. 7(9), 2009, 1858-1867
http://hdl.handle.net/123456789/588 |
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| Description |
A concise and general route to synthesize new class of [6-5-6] tricyclic core embedded polyheterocycles has been accomplished using diastereoselective Nazarov cyclization with an overall yield of 35-40%. Versatility of this synthetic route has also been demonstrated by accessing a variety of [6-5-5] tricyclic core incorporated polycycles. It was observed that the efficiency of cyclization depends upon the impact of polarization on the reacting systems. Amongst the various Lewis and Bronsted acids screened for cyclization, Triflic acid was found to be the most effective catalyst.
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187607 bytes
application/pdf |
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| Language |
en
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| Subject |
Taiwania cryptomerioide
abeo-abietane taiwaniaquinoids Taiwaniaquinol B [6-5-5] tricyclic Lewis and Bronsted acids |
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| Title |
Application of Nazarov cyclization to access [6-5-6] and [6-5-5]tricyclic core embedded New Heterocycles : An easy entry to structures related to Taiwaniaquinoids
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| Type |
Article
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