Application of phenolate ion-mediated intramolecular epoxide ring opening in the enantioselective synthesis of functionalized 2,3-dihydrobenzofuran and 1-benzopyran derivatives
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Dinda, S K
Das, S K Panda, Gautam |
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| Date |
2010-09-09T08:52:45Z
2010-09-09T08:52:45Z 2009 |
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| Identifier |
Synthesis, 2009, 11, 1886-1896
http://hdl.handle.net/123456789/590 |
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| Description |
The enantioselective synthesis of 2-isopropenyl-2,3-dihydrobenzofurans, 4-(2,3-dihydrobenzofuran-2-yl)-2-methylbut-3-en-2-ols, 2-hydroxymethylchromans, and 4-chroman-2-yl-2-methyl-but-3-en-2-ols has been achieved using Sharpless asymmetric epoxidation-derived enantiomerically enriched epoxy alcohols as chiral building blocks. A phenolate ion-mediated intramolecular epoxide ring opening reaction was the key step for every cyclization reaction.
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247815 bytes
application/pdf |
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| Language |
en
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| Subject |
2-isopropenyl-2,3-dihydrobenzofuran
2-hydroxymethyl chromans Epoxidation Epoxides Polycycles Ring opening |
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| Title |
Application of phenolate ion-mediated intramolecular epoxide ring opening in the enantioselective synthesis of functionalized 2,3-dihydrobenzofuran and 1-benzopyran derivatives
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| Type |
Article
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