Unprecedented ‘Bridged Annulation’ Approach to the Construction of 5,6-Dihydro-4H-benzo[kl]acridines
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Goel, Atul
Singh, S P Kumar, Amit Kant, Ruchir Maulik, P R |
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| Date |
2010-09-09T08:56:34Z
2010-09-09T08:56:34Z 2009 |
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| Identifier |
Org Lett. 2009, 11(22), 5122-5
http://hdl.handle.net/123456789/601 |
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| Description |
A general and novel ‘bridged annulation’ methodology for the synthesis of 5,6-dihydro-4H-benzo[kl]acridines has been developed via Michael addition of a conjugate base of 9-methyl-3,4-dihydroacridin-1(2H)-one to various cyclic or acyclic ,-unsaturated carbonyl/nitrile compounds under mild conditions at room temperature in a short time. To the best of our knowledge, such a general ‘bridged annulation’ for the synthesis of fused N-heterocycles has not been reported in the literature
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| Format |
106183 bytes
application/pdf |
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| Language |
en
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| Subject |
bridged annulation
N-heterocycles Quinoline acridine |
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| Title |
Unprecedented ‘Bridged Annulation’ Approach to the Construction of 5,6-Dihydro-4H-benzo[kl]acridines
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| Type |
Article
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