Cassane Diterpenes from Caesalpinia bonduc
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
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| Creator |
Yadava, P P
Maurya, Ranjani Sarkar, Jayanta Arora, Ashish Kanojiya, Sanjeev Sinha, Sudhir Srivastava, M N Raghubir, Ram |
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| Date |
2010-09-09T08:57:03Z
2010-09-09T08:57:03Z 2009 |
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| Identifier |
Phytochemistry,70(2)2009-256-261
http://hdl.handle.net/123456789/604 |
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| Description |
Three new cassane diterpene hemiketals, caesalpinolide-C (1), caesalpinolide-D (2), caesalpinolide-E (3) and one new cassane furanoditerpene (4) were isolated from Caesalpinia bonduc. Molecular structure of new compounds were elucidated using NMR spectroscopy in combination with IR, UV and mass spectral data and relative stereochemistries were determined through ROESY correlation. The isolated compounds were tested for their antiproliferative activity in MCF-7 (breast adenocarcinoma), DU145 (prostate carcinoma), C33A (Cervical carcinoma) and Vero (African green monkey kidney fibroblast) cells.
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| Format |
236000 bytes
application/pdf |
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| Language |
en
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| Subject |
Caesalpinia bonduc
Fabaceae phytochemistry cassane diterpenes butenolides furanoditerpenes antiproliferative activity |
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| Title |
Cassane Diterpenes from Caesalpinia bonduc
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| Type |
Article
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