Copper-catalyzed cascade reactions of substituted 4-iodo-pyrazolecarbaldehydes with 1,2-phenylenediamines and 2-aminophenols
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Nayak, Maloy
Batra, Sanjay |
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| Date |
2011-03-17T05:30:06Z
2011-03-17T05:30:06Z 2010 |
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| Identifier |
Adv. Synth. Catal. 2010, 352, 3431 – 3437
http://hdl.handle.net/123456789/649 |
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| Description |
A new approach for the synthesis of novel annulated-pyrazoles is presented. This protocol includes an intermolecular condensation followed by a copper-mediated intramolecular C-N or C-O coupling reaction. The method is applied to a range of substituted 4-iodopyrazolecarbaldehydes which react with 1,2-phenylenediamines or 2-aminophenols to yield substituted-2,4 or 1,4-dihydrobenzo[b]pyrazolo[4,3-e][1,4]diazepines or substituted-2H or 1H-benzo[b]pyrazolo[3,4-f][1,4]oxazepines, respectively.
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| Format |
183556 bytes
application/pdf |
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| Language |
en
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| Relation |
CDRI Communication No 7986
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| Subject |
Pyrazole
Copper C-N coupling C-O coupling diazepines oxazepines |
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| Title |
Copper-catalyzed cascade reactions of substituted 4-iodo-pyrazolecarbaldehydes with 1,2-phenylenediamines and 2-aminophenols
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| Type |
Article
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