Aza variant of intramolecular nucleophile-catalyzed aldol lactonization (NCAL): formal synthesis of (3S, 4R) and (3R, 4S) 4-(hydroxymethyl) pyrrolidin-3-ol
IR@CDRI: CSIR-Central Drug Research Institute, Lucknow
View Archive Info| Field | Value | |
| Creator |
Dikshit, D K
Sikriwal, Dimpy |
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| Date |
2011-06-24T09:19:00Z
2011-06-24T09:19:00Z 2011 |
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| Identifier |
Tetrahedron (2011), 67(17), 210-15
http://hdl.handle.net/123456789/691 |
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| Description |
Aza variant of intramolecular catalytic, asymmetric nucleophile-catalyzed, aldol lactonization (NCAL) reaction has been explored to synthesize β-lactone fused nitrogen heterocyclics as aza-sugars precursors by employing achiral amino acids. The utility of these bicyclic β-lactones is presented by the formal synthesis of aza-sugars, (3S, 4R) and (3R, 4S) 4-(hydroxymethyl) pyrrolidin-3-ol
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| Format |
372833 bytes
application/pdf |
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| Language |
en
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| Relation |
cdricommunication no.7983
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| Subject |
Aza sugars
Aza NCAL reaction Acetyl quinidine β-lactone O-Acetyl quinine |
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| Title |
Aza variant of intramolecular nucleophile-catalyzed aldol lactonization (NCAL): formal synthesis of (3S, 4R) and (3R, 4S) 4-(hydroxymethyl) pyrrolidin-3-ol
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Article
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