A Triterpenoid Saponin Possessing Antileishmanial Activity from the Leaves of Careya Arborea
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
A Triterpenoid Saponin Possessing Antileishmanial Activity from the Leaves of Careya Arborea
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| Creator |
Mandal, Debayan
Panda, Nilendu Kumar, Shrabanti Banerjee, Sukdeb Mondal, Nirup B Sahu, Niranjan P |
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| Subject |
Chemistry
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| Description |
Bioguided-fractionation of the methanol extract of the leaves of Careya arborea led to isolation of a triterpenoid saponin, designated arborenin, and characterized as 3-O-b-D-glucopyranosyl(1!2)-b-D-glucopyranosyl-2a,3b-dihydroxy-taraxast-20-en-28-oic acid (1), together with desacylescin III (2). The structures were determined on the basis of extensive 2D NMR spectroscopic analysis. The saponin
showed in vitro antileishmanial activity against Leishmania donovani (strain AG 83).
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| Date |
2006
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1083/1/PHYTOCHEMISTRY__Volume_67___Issue_2___Pages_183%2D190[145].pdf
Mandal, Debayan and Panda, Nilendu and Kumar, Shrabanti and Banerjee, Sukdeb and Mondal, Nirup B and Sahu, Niranjan P (2006) A Triterpenoid Saponin Possessing Antileishmanial Activity from the Leaves of Careya Arborea. Phytochemistry, 67 (2). pp. 183-190. |
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| Relation |
http://dx.doi.org/10.1016/j.phytochem.2005.10.028
http://www.eprints.iicb.res.in/1083/ |
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