A Simple One-Pot Entry to Cyclic Ethers of Varied Ring Sizes From Diols via Phosphonium Ion Induced Iodination and Base Catalyzed Williamson Etherification
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
A Simple One-Pot Entry to Cyclic Ethers of Varied Ring Sizes From Diols via Phosphonium Ion Induced Iodination and
Base Catalyzed Williamson Etherification
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| Creator |
Roy, Biswajit Gopal
Roy, Ashim Achari, Basudeb Mandal, Sukhendu B |
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| Subject |
Chemistry
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| Description |
A novel and an efficient one-pot cyclization method using triphenylphosphine, iodine and a nitrogenous base has
been established for the synthesis of cyclic ethers of various ring sizes. This appears to follow a two-step procedure, which includes
preferential substitution of one hydroxyl group by an iodide generated in situ followed by an intramolecular ring closure through the
attack of a free hydroxyl group or the more nucleophilic oxide ion.
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| Date |
2006
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1091/1/TETRAHEDRON_LETTERS__Volume_47___Issue_44___Pages_7783%2D7787___[22].pdf
Roy, Biswajit Gopal and Roy, Ashim and Achari, Basudeb and Mandal, Sukhendu B (2006) A Simple One-Pot Entry to Cyclic Ethers of Varied Ring Sizes From Diols via Phosphonium Ion Induced Iodination and Base Catalyzed Williamson Etherification. Tetrahedron Letters, 47 (44). pp. 7783-7787. |
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| Relation |
http://dx.doi.org/10.1016/j.tetlet.2006.08.090
http://www.eprints.iicb.res.in/1091/ |
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