microRNAs in viral oncogenesis
IR@IGIB: CSIR-Institute of Genomics & Integrative Biology, New Delhi
View Archive Info| Field | Value | |
| Title |
microRNAs in viral oncogenesis
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| Creator |
Scaria, Vinod
Jadhav, Vaibhav |
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| Subject |
G1 Genome informatics (General)
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| Description |
MicroRNAs are a recently discovered class of small noncoding functional RNAs. These molecules
mediate post-transcriptional regulation of gene expression in a sequence specific manner.
MicroRNAs are now known to be key players in a variety of biological processes and have been
shown to be deregulated in a number of cancers. The discovery of viral encoded microRNAs,
especially from a family of oncogenic viruses, has attracted immense attention towards the
possibility of microRNAs as critical modulators of viral oncogenesis. The host-virus crosstalk
mediated by microRNAs, messenger RNAs and proteins, is complex and involves the different
cellular regulatory layers. In this commentary, we describe models of microRNA mediated viral
oncogenesis.
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| Date |
2007-11-24
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://openaccess.igib.res.in/90/1/1742%2D4690%2D4%2D82.pdf
Scaria, Vinod and Jadhav, Vaibhav (2007) microRNAs in viral oncogenesis. Retrovirology, 4 (82). |
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| Relation |
http://openaccess.igib.res.in/90/
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