Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication
IR@IGIB: CSIR-Institute of Genomics & Integrative Biology, New Delhi
View Archive Info| Field | Value | |
| Title |
Human cellular microRNA hsa-miR-29a interferes with viral nef
protein expression and HIV-1 replication
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| Creator |
Ahluwalia, Jasmine K
Khan, Sohrab Zafar Soni, Kartik Rawat, Pratima Gupta, Ankit Hariharan, Manoj Scaria, Vinod Lalwani, Mukesh Pillai, Beena Mitra, Debashis Brahmachari, Samir K. |
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| Subject |
G1 Genome informatics (General)
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| Description |
Cellular miRNAs play an important role in the regulation of gene expression in
eukaryotes. Recently, miRNAs have also been shown to be able to target and inhibit viral gene
expression. Computational predictions revealed earlier that the HIV-1 genome includes regions
that may be potentially targeted by human miRNAs. Here we report the functionality of predicted
miR-29a target site in the HIV-1 nef gene.
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| Date |
2008-12-23
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://openaccess.igib.res.in/92/1/1742%2D4690%2D5%2D117.pdf
Ahluwalia, Jasmine K and Khan, Sohrab Zafar and Soni, Kartik and Rawat, Pratima and Gupta, Ankit and Hariharan, Manoj and Scaria, Vinod and Lalwani, Mukesh and Pillai, Beena and Mitra, Debashis and Brahmachari, Samir K. (2008) Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication. Retrovirology, 5 (117). |
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| Relation |
http://openaccess.igib.res.in/92/
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