Quadfinder: server for identification and analysis of quadruplex-forming motifs in nucleotide sequences
IR@IGIB: CSIR-Institute of Genomics & Integrative Biology, New Delhi
View Archive Info| Field | Value | |
| Title |
Quadfinder: server for identification and analysis of
quadruplex-forming motifs in nucleotide sequences
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| Creator |
Scaria, Vinod
Hariharan, Manoj Arora, Amit Maiti, Souvik |
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| Subject |
G1 Genome informatics (General)
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| Description |
G-quadruplex secondary structures, which play a structural role in repetitive DNA such as telomeres, may also play a functional role at other genomic locations as targetable regulatory elements which control gene expression. The recent interest in application of quadruplexes in biological systems prompted us to develop a tool for the identification and analysis of quadruplex-forming nucleotide sequences especially in the RNA. Here we present Quadfinder, an online server for prediction and bioinformatics of uni-molecular quadruplex-forming nucleotide sequences. The server is designed to be user-friendly and needs minimal intervention by the user, while providing flexibility of defining the variants of the motif. The server is freely available at URL http://miracle.igib.res.in/quadfinder/.
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://openaccess.igib.res.in/102/1/Nucl.%20Acids%20Res.%2D2006%2DScaria%2DW683%2D5.pdf
Scaria, Vinod and Hariharan, Manoj and Arora, Amit and Maiti, Souvik Quadfinder: server for identification and analysis of quadruplex-forming motifs in nucleotide sequences. PubMed, 34. |
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| Relation |
http://openaccess.igib.res.in/102/
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