Domino synthesis of indenols and alkyl-indene ethers under modified Vilsmeier conditions
IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu
View Archive Info| Field | Value | |
| Title |
Domino synthesis of indenols and alkyl-indene ethers under modified Vilsmeier conditions
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| Creator |
Singh, Parvinder Pal
Reddy, P. Bhaskar Sawant, Sanghapal D. Koul, S. Taneja, S.C. Kumar, H.M. Sampath |
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| Subject |
Chemical Sciences
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| Description |
Indenols are produced in high yields through domino reactions, when electron-rich trans-stilbenes and other trans aryl–alkyl olefins were subjected to Vilsmeier formylation in the presence of excess POCl3 in a one-pot procedure. The method is even suitable for converting aryl–alkyl carbinols (precursors for olefins) directly into indenols. The corresponding indene ethers could be
prepared in high yields directly when less reactive a,b-unsaturated aldehydes were subjected to cyclization in alcoholic HCl.
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| Date |
2006
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/241/1/10.1016j.tetlet.2006.07.126.pdf
Singh, Parvinder Pal and Reddy, P. Bhaskar and Sawant, Sanghapal D. and Koul, S. and Taneja, S.C. and Kumar, H.M. Sampath (2006) Domino synthesis of indenols and alkyl-indene ethers under modified Vilsmeier conditions. Tetrahedron Letters, 47 (40). pp. 7241-7243. ISSN 00404039 |
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| Relation |
http://dx.doi.org/10.1016/j.tetlet.2006.07.126
http://iiim.csircentral.net/241/ |
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