Anti-arthritic activity of a biopolymeric fraction from Euphorbia tirucalli
IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu
View Archive Info| Field | Value | |
| Title |
Anti-arthritic activity of a biopolymeric fraction from Euphorbia tirucalli
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| Creator |
Bani, Sarang
Kaul, Anpurna Khan, Beenish Gupta, Vijay Kumar Satti, Naresh Kumar Suri, Krishan Avtar Qazi, Ghulam Nabi |
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| Subject |
Pharmacological Sciences
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| Description |
The present study was undertaken to investigate the anti-arthritic activity of a biopolymeric fraction (BET) from plant Euphorbia tirucalli Boiss (Euphorbiaceae). The fraction showed dose dependent anti-arthritic activity and also showed in vivo immunomodulatory capacity being
a major component in inhibiting arthritis. It caused suppression of CD4+ and CD8+ T cells, inhibition of intracellular Interleukin-2 (IL-2) and Interferon-gamma (IFN-�) by flowcytometry. It inhibited vascular permeability and the migration of leucocytes at the site of the insult. The oral LD0 in both rats and mice was more than 2000 mg/kg.
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| Date |
2007
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/210/1/10.1016j.jep.2006.09.021.pdf
Bani, Sarang and Kaul, Anpurna and Khan, Beenish and Gupta, Vijay Kumar and Satti, Naresh Kumar and Suri, Krishan Avtar and Qazi, Ghulam Nabi (2007) Anti-arthritic activity of a biopolymeric fraction from Euphorbia tirucalli. Journal of Ethnopharmacology, 110 (1). pp. 92-98. ISSN 03788741 |
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| Relation |
http://dx.doi.org/10.1016/j.jep.2006.09.021
http://iiim.csircentral.net/210/ |
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