Effect of altitude on picroside content in core collections of Picrorhiza kurrooa from the north western Himalayas
IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu
View Archive Info| Field | Value | |
| Title |
Effect of altitude on picroside content in core collections of Picrorhiza kurrooa from the north western Himalayas
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| Creator |
Katoch, Meenu
Fazli, I. S. Suri, K. A. Ahuja, A. Qazi, G. N. |
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| Subject |
Biological Sciences
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| Description |
Picrorhiza kurrooa Royle ex Benth (Scrophulariaceae),
commonly known as Kutki, is a major ingredient of many ayurvedic preparations prescribed in the treatment of various diseases. Picrosides I and II are the active agents responsible for the medicinal effects of Kutki,and the variation in content of these compounds in plants at
different altitudes is a major question to be addressed. The
picroside I and II content in various plant parts of P. kurrooa collected from different altitudes, viz. Sonemarg
(2,740 m a.s.l.), Tangmarg (2,690 m a.s.l.), and Pulwama
(1,630 m a.s.l.) in the north-western Kashmir Himalayas
was analyzed by HPLC. A considerable degree of variation
in picroside content was observed. Picroside I and II was
highest in populations collected from Sonemarg followed
by Tangmarg, suggesting that picroside accumulation is
directly correlated with altitudinal change. More picroside
I was found in the rhizome and roots of the Pulwama
population as compared to Tangmarg samples, whereas the
quantity of Picroside II was reduced in plants from Pulwama
compared to the Tangmarg population, suggesting that
cultivation of P. kurroa at lower altitude reduces the
picroside content. The quantities of picrosides also varied
spatially, being highest in rhizome followed by roots,
inflorescence and leaves in the populations from all three
locations. The study concludes that picroside I and II
accumulation depends on altitude, which could help in the
selection and collection of superior genotypes with uniform
effects for utilization by the pharmaceutical industry.
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| Date |
2011
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/245/1/10.1007s11418%2D010%2D0491%2D9.pdf
Katoch, Meenu and Fazli, I. S. and Suri, K. A. and Ahuja, A. and Qazi, G. N. (2011) Effect of altitude on picroside content in core collections of Picrorhiza kurrooa from the north western Himalayas. Journal of Natural Medicines, 65 (3-4). pp. 578-582. ISSN 1340-3443 |
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| Relation |
http://dx.doi.org/10.1007/s11418-010-0491-9
http://iiim.csircentral.net/245/ |
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