Enantiomerically pure α-methoxyaryl acetaldehydes as versatile precursors: a facile chemo-enzymatic methodology for their preparation
IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu
View Archive Info| Field | Value | |
| Title |
Enantiomerically pure α-methoxyaryl acetaldehydes as versatile precursors: a facile chemo-enzymatic methodology for their preparation
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| Creator |
Singh, Buddh
Gupta, Pankaj Chaubey, Asha Parshad, Rajinder Sharma, Shiromani Taneja, Subhash C. |
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| Subject |
Chemical Sciences
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| Description |
A facile and efficient synthesis of optically active a-methoxyaryl acetic acids (up to 95% ee), a-methoxyaryl
ethanols (up to 93% ee) and a-methoxyaryl acetonitriles (up to 93% ee) was achieved via Arthrobacter sp. lipase-catalyzed kinetic resolution of masked aldehydes as the key synthons, that is, a-hydroxyaryl
acetaldehyde acetals.
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| Date |
2008
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/248/1/10.1016j.tetasy.2008.10.023.pdf
Singh, Buddh and Gupta, Pankaj and Chaubey, Asha and Parshad, Rajinder and Sharma, Shiromani and Taneja, Subhash C. (2008) Enantiomerically pure α-methoxyaryl acetaldehydes as versatile precursors: a facile chemo-enzymatic methodology for their preparation. Tetrahedron: Asymmetry, 19 (22). pp. 2579-2588. ISSN 09574166 |
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| Relation |
http://dx.doi.org/10.1016/j.tetasy.2008.10.023
http://iiim.csircentral.net/248/ |
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