Psilostachyin, acetylated pseudoguaianolides and their analogues: Preparation and evaluation of their anti-inflammatory potential
IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu
View Archive Info| Field | Value | |
| Title |
Psilostachyin, acetylated pseudoguaianolides and their analogues: Preparation and evaluation of their anti-inflammatory potential
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| Creator |
Shah, Bhahwal Ali
Chib, Renu Anand, Naveen Pandey, Anjali Kapoor, Kamini Bani, Sarang Gupta, Vivek K. K, Rajnikant Sethi, Vijay K. Taneja, Subhash Chandra |
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| Subject |
Chemical Sciences
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| Description |
Naturally occurring acetylated pseudoguaianolides and psilostachyin including their analogues were synthesized.
The structure of semi-synthetic psilostachyin was also confirmed by X-ray crystallography. The anti-inflammatory potential of all the derivatives has been evaluated through in vitro expression of TNF-a, IL-1b and IL-6 in murine neutrophils.
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| Date |
2011
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/320/1/10.1016j.bmcl.2011.06.037.pdf
Shah, Bhahwal Ali and Chib, Renu and Anand, Naveen and Pandey, Anjali and Kapoor, Kamini and Bani, Sarang and Gupta, Vivek K. and K, Rajnikant and Sethi, Vijay K. and Taneja, Subhash Chandra (2011) Psilostachyin, acetylated pseudoguaianolides and their analogues: Preparation and evaluation of their anti-inflammatory potential. Bioorganic & Medicinal Chemistry Letters, 21 (16). pp. 4847-4851. ISSN 0960894X |
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| Relation |
http://dx.doi.org/10.1016/j.bmcl.2011.06.037
http://iiim.csircentral.net/320/ |
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