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A long chain alkylated ;1-methylene-;3-butyrolactone from Artabotrys odoratissimus fruit

IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat

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Title A long chain alkylated ;1-methylene-;3-butyrolactone from Artabotrys odoratissimus fruit
 
Creator Bordoloi, P K
Bhuyan , P D
Baruah, P
Bordoloi, M J
Rao, P G
 
Subject Organic Chemistry
 
Description As part of our ongoing programme for isolation of bioactive molecules from the flora of the Indo-Burma biodiversity belt, an unusual long chain alkylated �-methylene-�-butyrolactone was isolated from the juice of ripe fruit of Artabotrys odoratissimus R.Br. Its structure was determined as 3-methylene-4-pentadecyldihydrofuran-2-one by spectroscopic methods. It was found to have good antifungal activity against Alternaria tenuissima Kunze Ex Pers. isolated from solasodine producing plant Solanum khasianum Clarke. Minimum Inhibitory Concentration (MIC)and IC50 for 3-methylene-4-pentadecyldihydrofuran-2-one were found as 300 and 51.37 ;Cg/ml, respectively. The standard captan was found to have an MIC and IC50 of 200 and 35.52 ;Cg/ml, respectively
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://neist.csircentral.net/73/1/2685_Phytochem_Lett2(1)p22%2D24.pdf
Bordoloi, P K and Bhuyan , P D and Baruah, P and Bordoloi, M J and Rao, P G A long chain alkylated ;1-methylene-;3-butyrolactone from Artabotrys odoratissimus fruit. Phytochemistry Letters, 2 (1). pp. 21-24.
 
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