Microwave promoted one-pot synthesis of novel A-ring fused steroidal dehydropiperazines
IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat
View Archive Info| Field | Value | |
| Title |
Microwave promoted one-pot synthesis of novel A-ring fused steroidal dehydropiperazines
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| Creator |
Borthakur, M
Barthakur, M G Boruah, R C |
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| Subject |
Organic Chemistry
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| Description |
The preparation of ring-A fused steroidal dehydropiperazine at the 3,4-position is herein
described. The novel steroidal dehydropiperazines were prepared from the annulation reaction
of ethylenediamine with 3-keto-4-en steroids in a one-pot reaction under microwave
irradiation. The key step involves base catalysed aerial oxidation of the C-6 methylene group
followed by cyclocondensation of ethylenediamine via Michael addition reaction.
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| Date |
2008
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://neist.csircentral.net/123/1/2570_Steroids73p539%2D42.pdf
Borthakur, M and Barthakur, M G and Boruah, R C (2008) Microwave promoted one-pot synthesis of novel A-ring fused steroidal dehydropiperazines. Steroids, 73 (5). pp. 539-542. |
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| Relation |
http://neist.csircentral.net/123/
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