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An efficient reduction protocol for the synthesis of beta-hydroxycarbamates from beta-nitro alcohols in one pot : a facile synthesis of (-)-beta-conhydrine

IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat

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Title An efficient reduction protocol for the synthesis of beta-hydroxycarbamates from beta-nitro alcohols in one pot : a facile synthesis of (-)-beta-conhydrine
 
Creator Saikia, P P
BAISHYA, G
Goswami, A
Barua, N C
 
Subject Organic Chemistry
 
Description An efficient and practical one-pot protocol for the reduction of b-nitro alcohols to their corresponding N-(tert-butoxycarbonyl) amino alcohols using Zn 13NH4Cl in aqueous methanol is described. Other reducible groups such as ketones and isolated double bonds remained intact. This methodology allows a short synthesis of (�)-b-conhydrine to be achieved.
 
Date 2008
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://neist.csircentral.net/146/1/2601_TETL49p.6508%2D11.pdf
Saikia, P P and BAISHYA, G and Goswami, A and Barua, N C (2008) An efficient reduction protocol for the synthesis of beta-hydroxycarbamates from beta-nitro alcohols in one pot : a facile synthesis of (-)-beta-conhydrine. Tetrahedrom Letters, 49. pp. 6508-6511.
 
Relation http://neist.csircentral.net/146/