An efficient reduction protocol for the synthesis of beta-hydroxycarbamates from beta-nitro alcohols in one pot : a facile synthesis of (-)-beta-conhydrine
IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat
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Title |
An efficient reduction protocol for the synthesis of beta-hydroxycarbamates from beta-nitro alcohols in one pot : a facile synthesis of (-)-beta-conhydrine
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Creator |
Saikia, P P
BAISHYA, G Goswami, A Barua, N C |
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Subject |
Organic Chemistry
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Description |
An efficient and practical one-pot protocol for the reduction of b-nitro alcohols to their corresponding
N-(tert-butoxycarbonyl) amino alcohols using Zn 13NH4Cl in aqueous methanol is described. Other
reducible groups such as ketones and isolated double bonds remained intact. This methodology allows
a short synthesis of (�)-b-conhydrine to be achieved.
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Date |
2008
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://neist.csircentral.net/146/1/2601_TETL49p.6508%2D11.pdf
Saikia, P P and BAISHYA, G and Goswami, A and Barua, N C (2008) An efficient reduction protocol for the synthesis of beta-hydroxycarbamates from beta-nitro alcohols in one pot : a facile synthesis of (-)-beta-conhydrine. Tetrahedrom Letters, 49. pp. 6508-6511. |
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Relation |
http://neist.csircentral.net/146/
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