A Simple and Practical Method for the Oxidation of Thebaine to 14-Hydroxycodeinone by V2O5–H2O2
IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat
View Archive Info| Field | Value | |
| Title |
A Simple and Practical Method for the Oxidation of Thebaine to
14-Hydroxycodeinone by V2O5–H2O2
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| Creator |
Das, Saikat Das
Konwar, D |
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| Subject |
Organic Chemistry
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| Description |
An efficient, practical and expeditious method has been
developed for the oxidation of thebaine to 14-hydroxycodeinone in
excellent yield by employing 20 mol% of V2O5 in the presence of
30% H2O2 in aqueous medium. The method provides a clean technological
process for the preparation of a key drug intermediate, 14-
hydroxycodeinone.
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| Date |
2009
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://neist.csircentral.net/169/1/2694synthesis_2009_7p1062%2D64.pdf
Das, Saikat Das and Konwar, D (2009) A Simple and Practical Method for the Oxidation of Thebaine to 14-Hydroxycodeinone by V2O5–H2O2. Synthesis (7). pp. 1061-1064. |
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| Relation |
http://neist.csircentral.net/169/
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