Compositional Variation in Bacterial Genes and Proteins With Potential Expression Level
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Compositional Variation in Bacterial Genes and Proteins
With Potential Expression Level
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| Creator |
Das, Sabyasachi
Ghosh, Subhagata Pan, Archana Dutta, Chitra |
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| Subject |
Structural Biology & Bioinformatics
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| Description |
Abstract Usage of guanine and cytosine at three codon sites in eubacterial genes vary distinctly with potential expressivity, as npredicted by Codon Adaptation Index (CAI). In bacteria with moderate/high GC-content, G3 follows a biphasic relationship, while C3 increases with CAI. In AT-rich bacteria, correlation of CAI is negative with G3, but non-speci.c with C3. Correlations
of CAI with residues encoded by G-starting codons are
positive, while with those by C-starting codons are usually negative/ random. Average Size/Complexity Score and aromaticity of gene-products decrease with CAI, con.rming general validity of cost-minimization principle in free-living eubacteria. Alcoholicity of bacterial gene-products usually decreases with expressivity.
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| Date |
2005
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1108/1/FEBS_LETTERS%2C_579(_23)%2C_5205%2D5210_[20].pdf
Das, Sabyasachi and Ghosh, Subhagata and Pan, Archana and Dutta, Chitra (2005) Compositional Variation in Bacterial Genes and Proteins With Potential Expression Level. FEBS Letters, 579 (23). pp. 5205-5210. |
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| Relation |
http://dx.doi.org/10.1016/j.febslet.2005.08.042
http://www.eprints.iicb.res.in/1108/ |
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