Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-, 12-, and 16-Membered Macrocyclic Scaffolds: Synthesis and Aggregation Study
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-, 12-, and 16-Membered Macrocyclic Scaffolds: Synthesis and
Aggregation Study
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| Creator |
Sengupta, Jhimli
Mukhopadhyay, Ranjan Bhattacharjya, Anup |
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| Subject |
Chemistry
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| Description |
Bis- and trisuracil nucleosides, in which the nucleobases are anchored to isoxazoline ring-fused 11-, 12-,
and 16-membered macrooxacycles, were synthesized by nucleosidation of 1,2-isopropylidenefuranose
ring-fused macrocycles. The nucleosides exhibited spherical and fiber-like morphologies in water. In
one case, the morphology was significantly altered by complexation with an adenine nucleoside via
complementary base pairing.
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| Date |
2007
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1145/1/JOURNAL_OF_ORGANIC_CHEMISTRY__72_(13)_4621%2D46252007;%7B75].pdf
Sengupta, Jhimli and Mukhopadhyay, Ranjan and Bhattacharjya, Anup (2007) Bis- and Trisuracil Nucleosides with Nucleobases Anchored to 11-, 12-, and 16-Membered Macrocyclic Scaffolds: Synthesis and Aggregation Study. The Journal of Organic Chemistry, 72 (13). pp. 4621-4625. |
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| Relation |
http://dx.doi.org/10.1021/jo062554b
http://www.eprints.iicb.res.in/1145/ |
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