KF/Al2O3 mediated 1,3-dipolar cycloaddition of azomethine ylides: a novel and convenient procedure for the synthesis of highly substituted pyrrolidines
IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat
View Archive Info| Field | Value | |
| Title |
KF/Al2O3 mediated 1,3-dipolar cycloaddition of azomethine ylides: a novel and convenient procedure for the synthesis of highly substituted pyrrolidines
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| Creator |
BORUAH , M
KONWAR, D SHARMA, S D |
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| Subject |
Organic Chemistry
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| Description |
—The regio- and diastereoselective synthesis of pyrrolidine derivatives through 1,3-dipolar cycloaddition of an azomethine
ylide and dipolarophile mediated by KF/Al 2O 3, a versatile solid supported reagent, is reported. KF/Al 2O 3 is sufficiently basic such
thatitcandeprotonatea-iminoesterstogenerateazomethineylidesanditalsofunctionsasasolidsupportedcatalystleadingtothe
cycloadduct rather than the Michael adduct.
2007 Elsevier Ltd. All rights reserved.
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| Date |
2007
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://neist.csircentral.net/250/1/2510_TL48_p.4535%2D37.pdf
BORUAH , M and KONWAR, D and SHARMA, S D (2007) KF/Al2O3 mediated 1,3-dipolar cycloaddition of azomethine ylides: a novel and convenient procedure for the synthesis of highly substituted pyrrolidines. Tetrahedron Letters, 48 (26). pp. 4535-4537. |
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| Relation |
http://neist.csircentral.net/250/
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