Penicillin Binding Proteins of Vibrio Cholerae
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Penicillin Binding Proteins of Vibrio Cholerae
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| Creator |
Sengupta, Tapas K
Chatterjee, Anadi N Das, Jyotirmoy |
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| Subject |
Infectious Diseases and Immunology
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| Description |
Eleven penicillin binding proteins (PBPs) of Vibrio cholerae have been identified
using [ ‘251] labelled p-hydroxybenzyl penicillin (PenX). These proteins are localised
in the inner membrane and have molecular weights ranging from 97,000 to 22,000.
Neutral hydroxylamine released the labelled PenX from the PBPs and pretreatment
with cold benzyl penicillin inhibited labelling completely. The PBP 4 is the most
sensitive target for cephaloridine and aztreonam. Cephaloridine also binds to
three other high molecular weight PBPs, 1, 2 and 3. Aztreonam, in addition to
PBP 4, has affinity for another low molecular weight PBP, PBP 7. Mecillinam
has affinity for PBPs 1, 4 and 11.
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| Publisher |
Elsevier
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| Date |
1990
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1209/1/BIOCHEMICAL_AND_BIOPHYSICAL_RESEARCH_COMMUNICATIONS__171(_3)_1175%2D1181;1990[13].pdf
Sengupta, Tapas K and Chatterjee, Anadi N and Das, Jyotirmoy (1990) Penicillin Binding Proteins of Vibrio Cholerae. Biochemical and Biophysical Research Communications, 171 (3). pp. 1175-1181. |
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| Relation |
http:..dx.doi.org/10.1016/0006-291X(90)90808-Z
http://www.eprints.iicb.res.in/1209/ |
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