Lipid a Mutants of Vibrio Cholerae: Isolation and Partial
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Lipid a Mutants of Vibrio Cholerae: Isolation and Partial
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| Creator |
Paul, Saptarshi
Sen, Asish K Banerjee, Nilima Chatterjee , Anadi N Das, Jyotirmoy |
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| Subject |
Chemistry
Infectious Diseases and Immunology |
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| Description |
Vibrio cholerae mutants resistant to common antibiotics and neutral and anionic
detergents were isolated. Analysis of isolated outer membranes revealed a sionificant
deficiency in the acylation of lipid A in the resistant strains. The contknt
of amide-linked and ester-bound fatty acids in the lipid A of the mutant strains
compared to that of the wild type was about 50-56% and 29-37% respectively.
This defect was specific for lipid A as there was no change in the acylation of
phospholipids. The reduction in fatty acid content of lipid A was reflected in
the altered endotoxic properties in the mutant strains.
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| Publisher |
Elsevier
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| Date |
1990
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1210/1/BIOCHEMICAL_AND_BIOPHYSICAL_RESEARCH_COMMUNICATIONS___169(1)_116%2D122;1990[37].pdf
Paul, Saptarshi and Sen, Asish K and Banerjee, Nilima and Chatterjee , Anadi N and Das, Jyotirmoy (1990) Lipid a Mutants of Vibrio Cholerae: Isolation and Partial. Biochemical and Biophysical Research Communications, 169 (1). pp. 116-122. |
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| Relation |
http://dx.doi.org/10.1016/0006-291X(90)91441-T
http://www.eprints.iicb.res.in/1210/ |
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