Reaction of allenylmagnesium and allenylindium bromides with nitrile oxides: synthesis of novel 5-butynyl- and 5-methylisoxazoles
IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu
View Archive Info| Field | Value | |
| Title |
Reaction of allenylmagnesium and allenylindium bromides with nitrile oxides: synthesis of novel 5-butynyl- and 5-methylisoxazoles
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| Creator |
Sampath Kumar, H.M.
Singh, Parvinder Pal Shafi, Syed Reddy, Pitta Bhaskar Shravankumar, Kankala Reddy, Doma Mahender |
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| Subject |
Chemical Sciences
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| Description |
5-Butynylisoxazoles were obtained in high yields through a domino addition, C–O heterocyclization involving allenylmagnesium bromide and benzonitrile oxide in dry THF, in which the corresponding 5-methylisoxazoles were isolated in trace amounts. However, when the reactions were attempted in aqueous media using allenylindium bromide, 5-methylisoxazoles were formed as the sole products in high yields.
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| Date |
2007
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/329/1/10.1016j.tetlet.2006.11.140.pdf
Sampath Kumar, H.M. and Singh, Parvinder Pal and Shafi, Syed and Reddy, Pitta Bhaskar and Shravankumar, Kankala and Reddy, Doma Mahender (2007) Reaction of allenylmagnesium and allenylindium bromides with nitrile oxides: synthesis of novel 5-butynyl- and 5-methylisoxazoles. Tetrahedron Letters, 48 (5). pp. 887-890. ISSN 00404039 |
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| Relation |
http://dx.doi.org/10.1016/j.tetlet.2006.11.140
http://iiim.csircentral.net/329/ |
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