Technetium-99m Amino Acid Chelates : Correlation of Their Physico-Chemical and Physiological Parameters . Part I .
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Technetium-99m Amino Acid Chelates :
Correlation of Their Physico-Chemical
and Physiological Parameters . Part I .
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| Creator |
Chakravarty, Munna
Sanyal, Soma Banerjee, Somenath |
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| Subject |
Infectious Diseases and Immunology
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| Description |
Ten a-aminocarboxylic acids were chelated with 99'"'Tc and purified by sephadex gel chromatography .
Their hepatobiliary and renal excretion patterns were determined in rats . It was observed that lipophilicity
of these chelates is the only determinant in governing their hepatobiliary excretion, whereas their renal
excretion is dependent on some other factors in addition to lipophilicity . Depression of renal excretion in
presence of probenecid indicated an interaction of renal tubular transport enzymes with these chelates,
which was explained from their hexacoordinated dioxotechnetium (V) chelate structure (II) .
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| Publisher |
Elsevier
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| Date |
1990
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://www.eprints.iicb.res.in/1223/1/JOURNAL_OF_INORGANIC_BIOCHEMISTRY__39_(_1)_43%2D57;1990[40].pdf
Chakravarty, Munna and Sanyal, Soma and Banerjee, Somenath (1990) Technetium-99m Amino Acid Chelates : Correlation of Their Physico-Chemical and Physiological Parameters . Part I . Journal of Inorganic Biochemistry, 39 (1). pp. 43-57. |
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| Relation |
http://dx.doi.org/10.1016/0162-0134(90)80014-O
http://www.eprints.iicb.res.in/1223/ |
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