Synthesis of new fluorescently labeled glycosylphosphatidylinositol (GPI) anchors
IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu
View Archive Info| Field | Value | |
| Title |
Synthesis of new fluorescently labeled glycosylphosphatidylinositol (GPI) anchors
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| Creator |
Saikam, Varma
Raghupathy, Riya Yadav, Mahipal Gannedi, Veeranjaneyulu Singh, Parvinder Pal Qazi, Naveed A. Sawant, Sanghapal D. Vishwakarma, Ram A. |
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| Subject |
Chemical Sciences
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| Description |
The borondipyrromethene (BODIPY) labeled new glycosylphosphatidylinositol (GPI) molecules were synthesized as cellular probes to study the chemical basis of microdomain organization of GPI-anchored proteins and cholesterol in plasma membrane. The synthesis enabled by a new stereo-selective glycosylation of myo-D-inositol acceptor led to the preparation of optically pure glucosaminyl-(1-6)-a-phosphatidylmyo-D-inositol and its unnatural stereoisomer.
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| Date |
2011
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://iiim.csircentral.net/355/1/10.1016j.tetlet.2011.06.005.pdf
Saikam, Varma and Raghupathy, Riya and Yadav, Mahipal and Gannedi, Veeranjaneyulu and Singh, Parvinder Pal and Qazi, Naveed A. and Sawant, Sanghapal D. and Vishwakarma, Ram A. (2011) Synthesis of new fluorescently labeled glycosylphosphatidylinositol (GPI) anchors. Tetrahedron Letters, 52 (33). pp. 4277-4279. ISSN 00404039 |
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| Relation |
http://dx.doi.org/10.1016/j.tetlet.2011.06.005
http://iiim.csircentral.net/355/ |
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