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Synthesis and biological screening of 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}- 3′-yl)-2-aryl-2,3-dihydro-1H-1,5-benzodiazepines

IR@IIIM: CSIR-Indian Institute of Integrative Medicine, Jammu

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Title Synthesis and biological screening of 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}- 3′-yl)-2-aryl-2,3-dihydro-1H-1,5-benzodiazepines
 
Creator Naqvi, Tahira
Mahajan, Deepali
Sharma, Rattan Lal
Khan, Inshad Ali
Kapoor, Kamal K.
 
Subject Chemical Sciences
 
Description A series of novel 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,50-isoxazoline-2}-30-yl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepines were synthesized. These molecules were screened in vitro for their antifungal and antibacterial activity, and none of the tested compounds showed promising antimicrobial or antifungal activity.
 
Date 2010
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://iiim.csircentral.net/351/1/10.1002jhet.194.pdf
Naqvi, Tahira and Mahajan, Deepali and Sharma, Rattan Lal and Khan, Inshad Ali and Kapoor, Kamal K. (2010) Synthesis and biological screening of 4-(3,3-dimethylspiro{bicyclo[2.2.1]heptan-2,5′-isoxazoline-2}- 3′-yl)-2-aryl-2,3-dihydro-1H-1,5-benzodiazepines. Journal of Heterocyclic Chemistry, 48 (1). pp. 144-148. ISSN 0022152X
 
Relation http://dx.doi.org/10.1002/jhet.194
http://iiim.csircentral.net/351/