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Studies on uracils : a facile one-pot synthesis of oxazino[4,5- d]-, pyrano[2,3-d]-, pyrido[2,3-d]- and pyrimido[4,5-d]pyrimidines using microwave irradiation in the solid state

IR@NEIST: CSIR-North East Institute of Science and Technology, Jorhat

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Title Studies on uracils : a facile one-pot synthesis of oxazino[4,5- d]-, pyrano[2,3-d]-, pyrido[2,3-d]- and pyrimido[4,5-d]pyrimidines using microwave irradiation in the solid state
 
Creator DEVI, I
BORAH , H N
BHUYAN , P J
 
Subject Organic Chemistry
 
Description —N,N-Dimethyl-5-formylbarbituric acid 1 reacts with maleimide 2 and phenyl isocyanate/phenyl isothiocyanate 4 under microwave-assisted conditions in the solid phase to afford pyrano[2,3-d]pyrimidines3 and oxazino[4,5-d]pyrimidines5 in excellent yields. Under identical conditions, N,N-dimethyl-6-amino-5-formyluracil 6 reacts with 2 and 4 to give pyrido[2,3-d]pyrimidine derivative 7 and pyrimido[4,5-d]pyrimidines 8 in high yields
 
Date 2004
 
Type Article
PeerReviewed
 
Format application/pdf
 
Identifier http://neist.csircentral.net/317/1/1143TL_2004_45p.2405.pdf
DEVI, I and BORAH , H N and BHUYAN , P J (2004) Studies on uracils : a facile one-pot synthesis of oxazino[4,5- d]-, pyrano[2,3-d]-, pyrido[2,3-d]- and pyrimido[4,5-d]pyrimidines using microwave irradiation in the solid state. Tetrahedron Letter, 45. pp. 2405-2408.
 
Relation http://neist.csircentral.net/317/