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Accessing microbial diversity for bioremediation and environmental restoration.

IR@IMTECH: CSIR-Institute of Microbial Technology, Chandigarh


Field	Value

Title	Accessing microbial diversity for bioremediation and environmental restoration.

Creator	Paul, Debarati Pandey, Gunjan Pandey, Janmejay Jain, R K

Subject	QR Microbiology

Description	Biological methods for decontamination promise an improved substitute for ineffective and costly physico-chemical remediation methods, although so far only a fraction of the total microbial diversity (i.e. the culturable fraction with metabolic potential) has been harnessed for this purpose. Exploring and exploiting the "overlooked" genetic resource might ameliorate concerns associated with the degradation of recalcitrant and xenobiotic pollutants that are not degraded or only poorly degraded by known culturable bacteria. Recent advances in the molecular genetics of biodegradation and in knowledge-based methods of rational protein modification provide insight into the development of "designer biocatalysts" for environmental restoration. The application of such genetically engineered microorganisms (GEMs) in the environment has been limited, however, owing to the risks associated with uncontrolled growth and proliferation of the introduced biocatalyst and horizontal gene transfer. Programming rapid death of the biocatalyst soon after the depletion of the pollutant could minimize the risks in developing these technologies for successful bioremediation.

Publisher	Elsevier Science

Date	2005-03

Type	Article PeerReviewed

Format	application/pdf

Identifier	http://crdd.osdd.net/open/185/1/jain2005.2.pdf Paul, Debarati and Pandey, Gunjan and Pandey, Janmejay and Jain, R K (2005) Accessing microbial diversity for bioremediation and environmental restoration. Trends in biotechnology, 23 (3). pp. 135-42. ISSN 0167-7799

Relation	http://www.sciencedirect.com/science/article/pii/S0167779905000235 http://crdd.osdd.net/open/185/