The Phenotype and Genotype Experiment Object Model (PaGE-OM): A Robust Data Structure for Information Related to DNA Variation
IR@IGIB: CSIR-Institute of Genomics & Integrative Biology, New Delhi
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Title |
The Phenotype and Genotype Experiment Object Model
(PaGE-OM): A Robust Data Structure for Information
Related to DNA Variation
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Creator |
Brookes, Anthony J.
Lehvaslaiho, Heikki Muilu, Juha Shigemoto, Yasumasa Oroguchi, Takashige Tomiki, Takeshi Mukaiyama, Atsuhiro Konagaya, Akihiko Kojima, Toshio Inoue, Ituro Kuroda, Masako Mizushima, Hiroshi Thorisson, Gudmundur A. Dash, Debasis Rajeevan, Haseena Darlison,, Matthew W Woon, Mark Fredman, David Smith, Albert V. Senger, Martin Naito, Kimitoshi Sugawara, Hideaki |
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Subject |
BI1 Bioinformatics (General)
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Description |
Torrents of genotype-phenotype data are being generated, all of which must be captured, processed, integrated, and exploited. To do this optimally requires the use of standard and interoperable "object models," providing a description of how to partition the total spectrum of information being dealt with into elemental "objects" (such as "alleles," "genotypes," "phenotype values," "methods") with precisely stated logical interrelationships (such as "A objects are made up from one or more B objects"). We herein propose the Phenotype and Genotype Experiment Object Model (PaGE-OM; www.pageom.org), which has been tested and implemented in conjunction with several major databases, and approved as a standard by the Object Management Group (OMG). PaGE-OM is open-source, ready for use by the wider community, and can be further developed as needs arise. It will help to improve information management, assist data integration, and simplify the task of informatics resource design and construction for genotype and phenotype data projects.
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Date |
2006-06
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Type |
Article
PeerReviewed |
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Format |
application/pdf
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Identifier |
http://openaccess.igib.res.in/125/1/PaGE%2DOM.pdf
Brookes, Anthony J. and Lehvaslaiho, Heikki and Muilu, Juha and Shigemoto, Yasumasa and Oroguchi, Takashige and Tomiki, Takeshi and Mukaiyama, Atsuhiro and Konagaya, Akihiko and Kojima, Toshio and Inoue, Ituro and Kuroda, Masako and Mizushima, Hiroshi and Thorisson, Gudmundur A. and Dash, Debasis and Rajeevan, Haseena and Darlison,, Matthew W and Woon, Mark and Fredman, David and Smith, Albert V. and Senger, Martin and Naito, Kimitoshi and Sugawara, Hideaki (2006) The Phenotype and Genotype Experiment Object Model (PaGE-OM): A Robust Data Structure for Information Related to DNA Variation. INFORMATICS, 30 (6). pp. 968-977. |
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Relation |
http://openaccess.igib.res.in/125/
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