Anticholinesterase Activity of Standardized Extract of Illicium Verum Hook. F. Fruits
IR@IICB: CSIR-Indian Institute of Chemical Biology, Kolkata
View Archive Info| Field | Value | |
| Title |
Anticholinesterase Activity of Standardized Extract of Illicium Verum Hook. F. Fruits
|
|
| Creator |
Bhadra, Santanu
Mukherjee, Pulok K Kumar, N Satheesh Bandyopadhyay, Arun |
|
| Subject |
Cell Biology & Physiology
|
|
| Description |
Illicium verum is a well known spice in traditional Indian system for its therapeutic potential. The
present study was aimed to evaluate the acetylcholinesterase (AChE) and butyrylcholinesterase
inhibitory (BChE) activity of standardized extracts of I. verum and its oil. Present study confirmed
that anethole contributed to the anticholinesterase activity of I. verum, with more specificity
towards AChE. IC50 for AChE and BChE inhibitory activity of anetholewas 39.89±0.32 μg/mL and
75.35±1.47 μg/mL, whereas for the oil, 36.00±0.44 μg/mL and 70.65±0.96 μg/mL respectively.
Therefore I. verum can be a good lead as anti-cholinesterase agent from natural resources.
|
|
| Publisher |
Elsevier
|
|
| Date |
2011
|
|
| Type |
Article
PeerReviewed |
|
| Format |
application/pdf
|
|
| Identifier |
http://www.eprints.iicb.res.in/1261/1/FITOTERAPIA__82(_3_)342%2D346;2011[115].pdf
Bhadra, Santanu and Mukherjee, Pulok K and Kumar, N Satheesh and Bandyopadhyay, Arun (2011) Anticholinesterase Activity of Standardized Extract of Illicium Verum Hook. F. Fruits. Fitoterapia, 82 (3). pp. 342-346. |
|
| Relation |
http://dx.doi.org/10.1016/j.fitote.2010.11.003
http://www.eprints.iicb.res.in/1261/ |
|