Chemical modification of L-glutamine to alpha-amino glutarimide on autoclaving facilitates Agrobacterium infection of host and non-host plants: A new use of a known compound
IR@IHBT: CSIR-Institute of Himalayan Bioresource Technology, Palampur
View Archive Info| Field | Value | |
| Title |
Chemical modification of L-glutamine to
alpha-amino glutarimide on autoclaving facilitates
Agrobacterium infection of host and non-host
plants: A new use of a known compound
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| Creator |
Sandal, I
Bhattacharya, Amita Saini, U Kaur, D Sharma , S Gulati, Ashu Kumar, J K Kumar, Neeraj Dayma, Joytsna Das, Pralay Singh , Bikram Ahuja, Paramvir Singh |
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| Subject |
Plant sciences
Natural Product Chemistry |
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| Description |
Abstract
Background: Accidental autoclaving of L-glutamine was found to facilitate the Agrobacterium infection of a non
host plant like tea in an earlier study. In the present communication, we elucidate the structural changes in Lglutamine
due to autoclaving and also confirm the role of heat transformed L-glutamine in Agrobacterium
mediated genetic transformation of host/non host plants.
Results: When autoclaved at 121°C and 15 psi for 20 or 40 min, L-glutamine was structurally modified into 5-oxo
proline and 3-amino glutarimide (a-amino glutarimide), respectively. Of the two autoclaved products, only a-amino
glutarimide facilitated Agrobacterium infection of a number of resistant to susceptible plants. However, the
compound did not have any vir gene inducing property.
Conclusions: We report a one pot autoclave process for the synthesis of 5-oxo proline and a-amino glutarimide
from L-glutamine. Xenobiotic detoxifying property of a-amino glutarimide is also proposed.
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| Date |
2011
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://ihbt.csircentral.net/942/1/31%2D01%2D2012_Chemical.pdf
Sandal, I and Bhattacharya, Amita and Saini, U and Kaur, D and Sharma , S and Gulati, Ashu and Kumar, J K and Kumar, Neeraj and Dayma, Joytsna and Das, Pralay and Singh , Bikram and Ahuja, Paramvir Singh (2011) Chemical modification of L-glutamine to alpha-amino glutarimide on autoclaving facilitates Agrobacterium infection of host and non-host plants: A new use of a known compound. Chemical Biology, 11. pp. 1-13. |
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| Relation |
http://ihbt.csircentral.net/942/
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