Antifungal Sesquiterpenes from Cedrus deodara
IR@IHBT: CSIR-Institute of Himalayan Bioresource Technology, Palampur
View Archive Info| Field | Value | |
| Title |
Antifungal Sesquiterpenes from
Cedrus deodara
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| Creator |
Chaudhary, A
Sood, S Kaur, P Kumar, Neeraj Thakur, A Gulati, Arvind Singh , Bikram |
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| Subject |
Plant sciences
Natural Product Chemistry |
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| Description |
Abstract
!
Two new sesquiterpenes, (E)-(2S,3S,6R)-atlantone-2,3-diol (1)
and (E)-(2S,3S,6S)-atlantone-2,3,6-triol (2), along with two
known sesquiterpenes, atlantolone (3) and (E)-α-atlantone (4),
were isolated from Cedrus deodara Loud. The structures of the
new compounds were elucidated on the basis of UV, IR, NMR,
HR‑ESI-QTOF‑MS, and EI mass spectral studies. The n-hexane
and chloroformextracts of sawdust and compounds 3 and 4 from
the plant exhibited antifungal activity against Aspergillus flavus,
A. niger, A. ochracoeus, A. parasiticus, and A. sydowii. A weak activity
was also recorded against A. parasiticus and A. sydowii for
compound 1, while Trichophyton rubrum was inhibited by compound
2 and the extracts.
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| Date |
2012
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://ihbt.csircentral.net/965/1/Planta_Medica_2012.pdf
Chaudhary, A and Sood, S and Kaur, P and Kumar, Neeraj and Thakur, A and Gulati, Arvind and Singh , Bikram (2012) Antifungal Sesquiterpenes from Cedrus deodara. Journal of Planta Medica, 78. pp. 186-188. |
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| Relation |
http://ihbt.csircentral.net/965/
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