Factors affecting podophyllotoxin yield in the ex situ grown Podophyllum hexandrum, an endangered alpine native of the western Himalayas
IR@IHBT: CSIR-Institute of Himalayan Bioresource Technology, Palampur
View Archive Info| Field | Value | |
| Title |
Factors affecting podophyllotoxin yield in the ex situ grown
Podophyllum hexandrum, an endangered alpine native
of the western Himalayas
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| Creator |
Kushwaha , R
Bhattacharya, Amita Singh , Bikram Singh, R D |
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| Subject |
Plant sciences
Natural Product Chemistry |
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| Description |
Abstract This study reports an appreciable yield of podophyllotoxin
(PDT) in P. hexandrum plants grown ex situ
under polyhouse conditions of a temperate locale. The PDT
content of below-ground parts was affected by both plant age
and growth period. However, only the effect of plant age on
PDT content was significant. Thus, the highest amounts of
PDT were recorded in the below-ground parts of 2-year-old
plants harvested during the late-growth period (LGP). High
total soluble sugars in the below-ground parts during the
early growth period (EGP) and the highest nitrate and nitrate
reductase in the leaves of 2-year-old plants during the peakgrowth
period (PGP) indicated higher mobilization and
assimilation of starch and nitrate. Probably the surplus carbon
and nitrogen gained during the PGP were diverted from
aerial parts to below-ground parts during the LGP and in turn
contributed to the synthesis of higher amounts of PDT. This
study shows that commercial cultivation of P. hexandrum is
possible under ex situ temperate conditions
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| Date |
2012
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://ihbt.csircentral.net/1048/1/52_Factors_affecting_2012.pdf
Kushwaha , R and Bhattacharya, Amita and Singh , Bikram and Singh, R D (2012) Factors affecting podophyllotoxin yield in the ex situ grown Podophyllum hexandrum, an endangered alpine native of the western Himalayas. J Nat Med, 66. pp. 1-7. |
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| Relation |
http://ihbt.csircentral.net/1048/
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