Functionalization of SBA-15 Mesoporous Materials using Thiol-Ene“Click” Michael Addition Reaction
IR@CECRI: CSIR-Central Electrochemical Research Institute, Karaikudi
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| Title |
Functionalization of SBA-15 Mesoporous Materials using Thiol-Ene“Click” Michael Addition Reaction
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| Creator |
Sushma, K.
Bharmana, M. Anal, K.G. Vijayamohanan, K.Pillai Gupta, S.S. |
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| Subject |
Electroinorganic
Electrochemical Analysis Electrochemical Materials Science |
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| Description |
Methacrylate-labeled SBA-15 has been successfully synthesized from calcined SBA-15 and commercially available 3-trichlorosilyl propylmethacrylate. This material undergoes efficient thiol-ene “click reaction” with a variety of both thiol- and disulfide-containing substrates in aqueous and organic media. The products were thoroughly characterized by a variety of analytical techniques including multinuclear (13C, 29Si)solid-state NMR, TG-DTA, and nitrogen adsorption desorption studies. Disulfide-containing substrates in which the TCEP mediated reduction of the disulfide bond and its subsequent addition to the methacrylate group anchored in SBA-15 in one-pot were used to synthesize a silica-protein hybrid material composed of biotin-labeled SBA-15 and streptavidin. Electrochemically active material was synthesized from the reaction of ferrocene-containing thiol and the methacrylate-labeled SBA-15. The ease of synthesis for the methacrylate-labeled
SBA-15 material together with its ability to undergo efficient chemoselective thiol-ene reaction would make it a very attractive
22 platform for the development of covalently anchored enzymes and sensors.
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| Publisher |
American Chemical Society
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| Date |
2011
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| Type |
Article
PeerReviewed |
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| Format |
application/pdf
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| Identifier |
http://cecri.csircentral.net/768/1/2011-009.pdf
Sushma, K. and Bharmana, M. and Anal, K.G. and Vijayamohanan, K.Pillai and Gupta, S.S. (2011) Functionalization of SBA-15 Mesoporous Materials using Thiol-Ene“Click” Michael Addition Reaction. Journal of Physical Chemistry C. 7.78. ISSN 1932-7447 |
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| Relation |
http://cecri.csircentral.net/768/
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